Diethylene Glycol Ethyl Ether
BOXA SOLVENTS
Butanal
Diethylene Glycol Ethyl Ether
Specifications
product_name Diethylene glycol ethyl ether
CAS_number 111-90-0
formula C6H14O3
molar_mass 134.17 g/mol
boiling_point 202-204°C
density 0.991 g/cm³
flash_point 98°C
refractive_index 1.4318
viscosity 3.68 cP at 25°C
vapor_pressure 0.02 mmHg at 25°C
water_solubility miscible
appearance clear, colorless liquid
odor mild ether-like
melting_point -68.1°C
surface_tension 28.0 dyn/cm at 20°C
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Frequently Asked Questions
What is Diethylene Glycol Ethyl Ether and what are its common applications?

Diethylene glycol ethyl ether, often known by its chemical name or as Transcutol or Carbitol, is a colorless, odorless, and hygroscopic liquid that is used in a wide variety of industrial and commercial applications due to its excellent solvent properties. It is composed of ethylene glycol ethers, making it a versatile compound in numerous formulations. One common application of diethylene glycol ethyl ether is in the field of pharmaceuticals, where it serves as an efficient solubilizer and penetration enhancer in topical gels, creams, and ointments. Its ability to enhance the penetration of active ingredients through the skin makes it invaluable in transdermal drug delivery systems. Additionally, its low toxicity profile tends to make it preferable for applications that require direct or indirect human contact.

Moreover, diethylene glycol ethyl ether finds widespread use in the realm of personal care products. It is employed as a solvent and stabilizer in the formulation of perfumes, skin care products, and hair care goods. The ether effectively dissolves fragrances and other ingredients, thereby improving the stability and texture of the products. In the coatings and paints industry, diethylene glycol ethyl ether functions as a coalescing agent. It is responsible for improving the flow and finish of water-based paints, leading to a smooth, uniform coating upon drying. Its high boiling point and good miscibility with water and organic solvents make it an optimal choice for achieving the desired consistency and performance in paints and coatings.

The compound is also present in a variety of cleaning solutions and detergents. Its solvent properties enable it to dissolve grease and oils efficiently, thus enhancing the cleaning power of detergents. In agricultural and household pesticides, diethylene glycol ethyl ether acts as a solvent and carrier for active ingredients. It helps in the even distribution and absorption of pesticides on plant surfaces. Furthermore, in textiles, it is used as a dye carrier and humectant, facilitating the dyeing process and maintaining fabric moisture to ensure optimal finish. Industrial applications of diethylene glycol ethyl ether include its role as a component in hydraulic and brake fluids, where it serves to improve viscosity and stability under varying temperature conditions. These diverse applications highlight the importance of diethylene glycol ethyl ether in various industries, owing largely to its multifaceted properties as an effective and efficient solvent.

Is Diethylene Glycol Ethyl Ether safe for use in consumer products?

The safety profile of diethylene glycol ethyl ether has been extensively studied and it is generally considered safe for use in consumer products when handled according to specified guidelines. The compound's low toxicity level is a contributing factor to its inclusion in many personal care and pharmaceutical products. Nevertheless, it is crucial to understand that the safety of diethylene glycol ethyl ether—or any chemical compound—highly depends on the concentration used and adherence to safety protocols. In topical applications, it acts as a penetration enhancer to facilitate the absorption of active compounds, and in this context, it is considered safe when used in recommended amounts.

For consumer products like cosmetics and personal care items, diethylene glycol ethyl ether is included in formulations based on its capacity to improve product efficacy, texture, and stability. Regulatory authorities in various regions, such as the U.S. Food and Drug Administration (FDA) and the European Chemicals Agency (ECHA), monitor and regulate the concentration of such compounds permissible in consumer goods to ensure safety. Manufacturers are required to comply with these regulations and conduct safety assessments for their products.

When it comes to occupational exposure, safety guidelines must be diligently followed. Workers handling diethylene glycol ethyl ether in industrial settings should utilize personal protective equipment (PPE) like gloves and goggles, and ensure adequate ventilation to prevent inadvertent inhalation or contact with skin and eyes. Long-term exposure, however, should be monitored according to workplace health and safety standards, as excessive exposure can potentially lead to adverse health effects.

In household and industrial products such as cleaning agents, paint, and coatings, diethylene glycol ethyl ether is intended for external use and typically poses minimal risk to consumers when used as directed. The safety instructions on product labels should be followed meticulously to avoid any unnecessary exposure.

While diethylene glycol ethyl ether is safe under controlled conditions, improper use or exposure beyond recommended limits can pose risks. Toxicological assessments and continuous monitoring by regulatory bodies help ensure that products on the market containing this compound remain within the safety parameters. Thus, when used properly and according to guidelines, diethylene glycol ethyl ether is regarded as safe for inclusion in various consumer products.

What are the environmental impacts of Diethylene Glycol Ethyl Ether?

Diethylene glycol ethyl ether has certain environmental impacts that are significant to consider, especially given its widespread use in various industrial and consumer applications. As with many chemical compounds, the environmental implications of diethylene glycol ethyl ether revolve around its release into the environment, potential bioaccumulation, and effects on aquatic and terrestrial ecosystems. Its biodegradability is a positive aspect that moderates some of the environmental concerns, but it does not entirely negate its ecological footprint.

Primarily, diethylene glycol ethyl ether is considered to have a moderate risk of aquatic toxicity. This compound can enter water bodies through industrial discharge, improper disposal, and runoff from products that contain it. In aquatic environments, it acts as a solvent, and although diethylene glycol ethyl ether is biodegradable, its presence in significant concentrations can still be harmful to aquatic organisms. The compound can affect the reproductive and development cycles of aquatic fauna if it accumulates in sufficient quantities. Regular monitoring of water bodies near industrial sites is often conducted to prevent notable environmental degradation.

Its vapor pressure is low, reducing the likelihood of significant volatilization into the atmosphere. However, should the compound become airborne, it can contribute to air pollution when subjected to photochemical reactions, although to a lesser extent than volatile organic compounds with higher vapor pressures. Despite this, air quality monitoring in areas with substantial industrial usage of diethylene glycol ethyl ether is vital to ensure mitigation of potential atmospheric impacts.

Regarding terrestrial environments, the impact is usually minimal due to its relatively low soil adsorption coefficient, suggesting that it is not very stable in soil environments and is more likely to leach into groundwater systems than accumulate on the surface. However, any substantial spillage of diethylene glycol ethyl ether needs immediate containment and remediation measures to prevent seepage into the soil, which could indirectly affect plant and microbial life.

As a part of responsible manufacturing and utilization, companies using diethylene glycol ethyl ether implement strict waste management and effluent treatment processes to limit the environmental impact. Many industries adhere to environmental regulations and guidelines set forth by regulatory bodies, such as the U.S. Environmental Protection Agency (EPA) and European Environment Agency (EEA), to minimize harmful emissions and discharge. Overall, while diethylene glycol ethyl ether is not classified as a highly environmentally hazardous material, its industrial usage demands careful management of its waste streams to prevent adverse ecological consequences.

How does Diethylene Glycol Ethyl Ether function as a solvent in various industries?

Diethylene glycol ethyl ether serves as an exceptional solvent across a wide range of industries due to its unique chemical and physical properties. It has a high boiling point, low volatility, good miscibility with water and many organic compounds, and a moderate dielectric constant. These characteristics render it highly effective at dissolving both polar and non-polar substances, making it invaluable for diverse industrial applications.

In the pharmaceutical industry, diethylene glycol ethyl ether is used as a solvent and carrier in the formulation of drugs, especially in topical and transdermal systems. It assists in dissolving both active pharmaceutical ingredients and excipients, ensuring that they are uniformly distributed throughout the formulation. Its ability to modify the solubility and permeability of active ingredients contributes to increased bioavailability, essentially enhancing drug efficacy.

In the paint and coatings industry, the solvent capabilities of diethylene glycol ethyl ether are critical. It acts as a coalescing agent in water-based paints, aiding in the formation of a continuous film. The high boiling point of diethylene glycol ethyl ether ensures a gradual evaporation process, which is essential for optimum film formation and finish, improving the durability and appearance of the painted surface. Furthermore, its compatibility with a wide range of resins and polymers allows paint formulators to develop coatings with desired gloss, flow, and leveling qualities.

In the realm of personal care and cosmetics, diethylene glycol ethyl ether is employed as a solvent in fragrances, creams, and lotions. It helps dissolve various ingredients, enhancing the stability and texture of these products. In perfumes, it is crucial for dissolving and stabilizing fragrance oils, allowing the final product to maintain a consistent aroma profile over time. Moreover, in skincare formulations, it acts as both a solvent and a humectant, retaining moisture in products and on the skin.

Industrial applications benefit from diethylene glycol ethyl ether’s solvent properties as well, specifically in cleaners and degreasers, where it efficiently dissolves oils and greases. This essential solvent property makes it a key ingredient in formulations designed for heavy-duty cleaning of industrial machinery, automotive parts, and other metal surfaces.

In the realm of agriculture, diethylene glycol ethyl ether serves as a solvent and carrier for pesticide formulations. It aids in solubilizing active ingredients and enhancing their stability and effectiveness, which is critical for achieving effective pest control.

Overall, diethylene glycol ethyl ether’s versatility as a solvent is evident in its ability to improve product performance across numerous industries. Its ability to act as both a solvent and co-solvent, coupled with its excellent compatibility with other formulation components, underscores its significance in product formulation and development in varied fields.

Are there any substitutes for Diethylene Glycol Ethyl Ether in industrial applications?

In the pursuit of improving sustainability, performance, or cost-effectiveness, industries often explore substitutes for commonly used compounds, including diethylene glycol ethyl ether. While it is widely valued for its excellent solvent properties, there are alternatives available that can be employed depending on the specific requirements of a given application. Selection of a substitute is guided by factors such as desired chemical properties, regulatory compliance, safety profiles, and performance outcomes.

In certain pharmaceutical and cosmetic applications, propylene glycol or glycerin might be considered as alternatives. Glycerin, with its humectant and emollient properties, is used extensively in personal care products, albeit with different solvent capacity. Propylene glycol serves as a solvent and penetration enhancer like diethylene glycol ethyl ether, frequently used in topical preparations and offering a different toxicological profile. However, the decision to switch to such substitutes involves evaluating the differences in solvent power, moisture retention, and interaction with other formulation components, as each compound carries distinct characteristics.

In the context of the paint and coatings industry, various glycol ethers may serve as potential substitutes. For instance, dipropylene glycol methyl ether (DPM) and tripropylene glycol methyl ether (TPM) are glycol ethers with similar solvent properties that can be used to achieve comparable results in water-based paint formulations. These substitutes might differ in terms of evaporation rates or regulatory status, which must be considered during a formulation change.

Industrial cleaners and degreasers might contain other solvents such as isopropanol or n-butyl alcohol as substitutes, depending on the specific cleaning power required. These are generally more volatile than diethylene glycol ethyl ether, thus requiring careful handling and formulation adjustments to maintain cleaning efficacy while controlling vapor pressure and flammability characteristics.

It is important to note that when opting for substitutes, comprehensive evaluation is necessary regarding safety profiles and environmental impacts. Substitute chemicals should adhere to regulatory standards specific to the industry and region to ensure continued compliance with health and safety regulations.

For agricultural applications where diethylene glycol ethyl ether is used as a solvent in pesticide formulations, alternatives like non-ionic surfactants or vegetable-based solvents may be considered to improve the biodegradability and reduce environmental impact. However, such replacements must be scrutinized for compatibility with active ingredients, stability under varying conditions, and efficacy on target pests.

Ultimately, while alternatives exist, there is no one-size-fits-all substitute for diethylene glycol ethyl ether. Each potential substitute presents its benefits and drawbacks, which need to be critically analyzed in the context of specific application requirements. Companies may conduct extensive research and pilot testing to ensure that selected alternatives perform as needed without compromising product quality, safety, or compliance standards.
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